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SEMAXA synthetic analog of ACTH(4-7) researched for neuroprotection, cognitive enhancement, and BDNF upregulation.
Semax is a heptapeptide analog of the ACTH(4-7) fragment developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It has been approved in Russia for stroke, cognitive impairment, and optic nerve disease. Research demonstrates robust BDNF and NGF upregulation, neuroprotection against ischemic damage, memory and learning enhancement, and anxiolytic effects.