KISSA naturally occurring neuropeptide that acts as a key regulator of GnRH secretion and the hypothalamic-pituitary-gonadal axis.
Kisspeptin-10 is the shortest biologically active fragment of kisspeptin (Kiss1 gene product), consisting of 10 amino acids. It is a potent activator of GnRH neurons, triggering a cascade of reproductive hormone release including LH and FSH. Research applications include fertility studies, HPG axis investigation, puberty onset mechanisms, and sex hormone regulation.