CAGRA long-acting amylin receptor agonist researched for satiety and weight management in combination with semaglutide (CagriSema).
Cagrilintide is an investigational long-acting amylin analog designed for weekly subcutaneous administration. It acts on amylin receptors in the brain to promote satiety and slow gastric emptying. The CagriSema combination (cagrilintide + semaglutide) has shown remarkable weight loss outcomes of up to 22.7% in REDEFINE clinical trials, demonstrating the synergistic potential of dual amylin/GLP-1 receptor activation.